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China Journal of Chinese Materia Medica ; (24): 1762-1765, 2007.
Article in Chinese | WPRIM | ID: wpr-287901

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the chemical constituents of Pyrola calliatha.</p><p><b>METHOD</b>The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral data.</p><p><b>RESULT</b>Ten compounds were isolated and identified as chimaphilin (1), uvaol(2), ursolic acid (3), 2beta,3beta,23-trihydroxy-12-ene-28-ursolic acid (4), daucosterol (5), 2alpha,3beta,23,24-tetrahydroxy-12-ene-28-ursolic acid (6), emodin (7), gallic acid (8), monotropein (9), adenosine (10).</p><p><b>CONCLUSION</b>Compounds 2,4,6,7,10 were obtained from this genus for the first time, compounds 5, 9 were obtained from this species for the first time. Antifungal activity of compounds 1-4, 6-9 were evaluated. Compound 1 showed the strong activity.</p>


Subject(s)
Antifungal Agents , Chemistry , Pharmacology , Cryptococcus neoformans , Iridoids , Chemistry , Pharmacology , Naphthoquinones , Chemistry , Pharmacology , Plants, Medicinal , Chemistry , Pyrola , Chemistry , Triterpenes , Chemistry , Pharmacology
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